Autoantibodies against glutamate receptor δ2 after allogenic stem cell transplantation

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Autoantibodies against glutamate receptor δ2 after allogenic stem cell transplantation

OBJECTIVE To report on a Caucasian patient who developed steroid-responsive transverse myelitis, graft vs host disease of the gut, and anti-GluRδ2 after allogenic stem cell transplantation. METHODS Histoimmunoprecipitation (HIP) with the patient's serum and cryosections of rat and porcine cerebellum followed by mass spectrometry was used to identify the autoantigen. Correct identification was...

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Background Stem cell transplantation has become as a novel treatment  for end-stage kidney, lung, heart , liver diseases and several hematologic disorders. Improved survival of transplant recipients has raised awareness of post-transplant complications. One of these complications is transplant-related osteoporosis. Methods  In this manuscript we review prevention methods for transplant-relat...

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Relationship between Molecular Chimerism and Graft Versus Host Disease after Allogenic Hematopoietic Stem Cell Transplantation

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ژورنال

عنوان ژورنال: Neurology - Neuroimmunology Neuroinflammation

سال: 2016

ISSN: 2332-7812

DOI: 10.1212/nxi.0000000000000255